Infx-PGx

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Pharmacogenomic Test for Drugs Related to Infectious Diseases

This PGx test uses a simple cheek swab to test a combination of genes related to the metabolism of drugs used in the management of a range of infections caused by different types of viruses, bacteria, fungi, protozoa and parasites. PGx testing is available for drugs used in the treatment of infectious diseases like malaria, HIV, candidiasis, aspergillosis, meningitis, leprosy, dermatitis herpetiformis, acne, after-burn skin infections, urinary tract infections, hepatitis C, and HIV AIDS.

If you are currently taking one of the following drugs, FDA recommends getting tested to determine if you have a gene mutation that could render a drug ineffective, cause unwanted side effects or result into a life-threatening event. Based on this information, your healthcare provider can suggest a different drug that can be safer and more effective. 

For further understanding, please refer to the United States FDA recommendations on Pharmacogenomic Biomarkers in Drug Labeling.

DRUG

GENE

Primaquine (2) 

CYB5R

Efavirenz

CYP2B6

Voriconazole

CYP2C19

Quinine Sulfate (2)

CYP2D6

Ceftriaxone (1)

G6PD

Chloroquine

G6PD

Dapsone (3)

G6PD

Erythromycin and Sulfisoxazole

G6PD

Hydroxychloroquine

G6PD

Mafenide

G6PD

Nalidixic Acid

G6PD

Nitrofurantoin

G6PD

Primaquine (1)

G6PD

Quinine Sulfate (1)

G6PD

Sulfadiazine

G6PD

Sulfamethoxazole and Trimethoprim (1)

G6PD

Tafenoquine

G6PD

Abacavir

HLA-B

Boceprevir

IFNL3 (IL28B)

Daclatasvir

IFNL3 (IL28B)

Dasabuvir, Ombitasvir, Paritaprevir, and Ritonavir

IFNL3 (IL28B)

Elbasvir and Grazoprevir

IFNL3 (IL28B)

Ledipasvir and Sofosbuvir

IFNL3 (IL28B)

Ombitasvir, Paritaprevir, and Ritonavir

IFNL3 (IL28B)

Peginterferon Alfa-2b

IFNL3 (IL28B)

Simeprevir

IFNL3 (IL28B)

Sofosbuvir

IFNL3 (IL28B)

Sofosbuvir and Velpatasvir

IFNL3 (IL28B)

Sofosbuvir, Velpatasvir, and Voxilaprevir

IFNL3 (IL28B)

Telaprevir

IFNL3 (IL28B)

Ceftriaxone (2)

Nonspecific (Congenital Methemoglobinemia)

Isoniazid, Pyrazinamide, and Rifampin

Nonspecific (NAT)

Sulfamethoxazole and Trimethoprim (2)

Nonspecific (NAT)

Dolutegravir

UGT1A1

Raltegravir

UGT1A1