Hemo-PGx

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Pharmacogenomic Test for Drugs Related to Blood Disorders

This PGx test uses a simple cheek swab to test a combination of genes related to the metabolism of drugs used in the management of a range of blood-related disorders like thrombocytopenia, myelodysplastic syndrome (MDS), multiple myeloma, and mantle cell lymphoma (MCL), aplastic anemia, blood clots, methemoglobinemia, lead poisoning, and hemophagocytic lymphohistiocytosis.

If you are currently taking one of the following drugs, FDA recommends getting tested to determine if you have a gene mutation that could render a drug ineffective, cause unwanted side effects or result into a life-threatening event. Based on this information, your healthcare provider can suggest a different drug that can be safer and more effective. 

For further understanding, please refer to the United States FDA recommendations on Pharmacogenomic Biomarkers in Drug Labeling.

DRUG

GENE

Eltrombopag (4)

Chromosome 13del

Lenalidomide

Chromosome 5q

Eltrombopag (3)

Chromosome 7del

Avatrombopag (6)

CYP2C9

Warfarin (1)

CYP2C9

Avatrombopag (1)

F2 (Prothrombin)

Lusutrombopag (1)

F2 (Prothrombin)

Avatrombopag (2)

F5 (Factor V Leiden)

Eltrombopag (1)

F5 (Factor V Leiden)

Lusutrombopag (2)

F5 (Factor V Leiden)

Methylene Blue

G6PD

Succimer

G6PD

Emapalumab-lzsg

PRF1, RAB27A, SH2D1A, STXBP2, STX11, UNC13D, XIAP (Hemophagocytic Lymphohistiocytosis)

Avatrombopag (3)

PROC

Lusutrombopag (3)

PROC

Warfarin (4)

PROC

Avatrombopag (4)

PROS1

Lusutrombopag (4)

PROS1